| Protocol No. | Title | Status |
| 06-0456-10 | Renal Tumors Classification, Biology and Banking Study | Open |
| 06-0665-10 | COG AREN0321: Treatment of High Risk Renal Tumors: A Groupwide Phase II Study | Open |
| 07-0414-10 | COG AREN0533: Treatment of Newly Diagnosed Higher Risk Favorable Histology Wilms Tumor | Open |
| 09-0907-04 | Treatment for Patients with Bilateral, Multicentric, or Bilaterally-Predisposed Unilateral Wilms Tumor: A Groupwide Phase III Study | Open |
| 11-0582-10 | SWOG 0931 “EVEREST: EVErolimus for Renal Cancer Ensuing Surgical Therapy, A Phase III Study | Open |
| 12-0988-04 | S1107 Parallel (Randomized) Phase II Evaluation of ARQ 197 and ARQ 197 in Combination with Erlotinib in Papillary Renal Cell Carcinoma | Open |