| Protocol No. | Title | Status |
| 02-0785-01 | CORE A: TISSUE RESOURCE (SPORE IN GI CANCER) | Open |
| 06-0101-03 | Sentinel Lymph Node Working Group Data Acquisition Project | Open |
| 07-0607-04 | A Study of the Effect of Vitamin E and/or Selenium on Adenomatous Colorectal Polyps in Patients Enrolled in the SELECT Trial, Ancillary to S0000 - SELECT | Open |
| 08-0819-04 | Phase IIa Clinical Biomarker Trial of Aspirin and Arginine Restriction in Colon Cancer Patients (Tissue Ancillary) | Open |
| 09-0118-03 | HR-QOL in Colorectal Cancer Survivors with Stomas (Renewal) | Open |
| 10-0006-04 | S0713 “A Phase II Study of Oxaliplatin, Capecitabine, Cetuximab and Radiation in Pre-Operative Therapy Of Rectal Cancer” | Open |
| 13-0030-04 | S0820 A Double Blind Placebo-Controlled Trial of Eflornithine and Sulindac to Prevent Recurrence of High Risk Adenomas and Second Primary Colorectal Cancers in Patients with Stage 0-III Colon Cancer, Phase III". | Open |